Dr. François Quenet

Dr. François Quénet

Peritoneal Carcinomatosis, tumors of the liver and bile ducts and retroperitoneal sarcomas.

Expert in digestive and hepatobiliary surgery.   Dr Quénet directs treatment Programmes of Peritoneal Carcinomatosis using Surgery plus Intraperitoneal Hyperthermal Chemotherapy (HIPEC).   He is the Principal Investigator of the phase III clinal trial “Prodige 7” investigating HIPEC for colorectal cancer.   He is a member of the INSERM research team U896 and works on the molecular basis for anti-tumoral drug resistance.

  • Doctor of Medicine, DES in General Surgery, Visceral Surgery, Faculty of Medicine of Montpellier.
  • Former intern of Montpellier hospitals. Oppositions 1986
  • Former chief of surgical clinic at the Faculty of Medicine of Montpellier.

Surgical oncologist at the Centre de Lutte contre le Cancer de Montpellier (ICM), since 1995.

Clinical functions:

  • Head of the Hepatobiliary Surgery and Peritoneal Carcinomatosis Unit of the ICM Surgery Department.
  • Responsible CPR “liver tumors”.
  • Responsible for supraregional CPR to the peritoneal carcinomatosis in the framework of the network RENAPE.
  • Responsible onco-vascular CPR in adult surgery and pediatric surgery at the Hospital Universitario de Montpellier.


Institutional functions:

  • Animation of the “Research-Innovation” cell of the ICM.
  • Responsible for the scientific coordination of SIRIC-Montpellier for peritoneal carcinomatosis.
  • Responsible for the clinical-biological basis “peritoneal carcinomatosis”.
  • Former national secretary of the group of surgeons of the centers, from 2008 to 2012.

Work areas:

  • Responsible for treatment of peritoneal carcinosis programs since 1995, which allows ICM to be the RENAPE reference center from the beginning.
  • Development of the PIPAC program (chemotherapy with intraperitoneal pressure aerosol) ICM since May 2016.
  • Specialized in the treatment of tumors of the liver and bile ducts, especially in surgery for liver metastases.
  • Specialized in surgery of retroperitoneal tumors of complex exeresis through the development of surgical techniques in multidisciplinary team of oncology and vascular.

Clinical research: Peritoneal carcinomatosis

Own studies to the team: 

  • Principal investigator of the multicenter phase III “PRODIGY 7” research: evaluate the role of intraoperative intraperitoneal chemotherapy (HIPEC) after maximum resection of peritoneal carcinomatosis of colorectal origin.
  • Principal investigator of the “NIPOX” phase I study: Induction therapy by intraperitoneal oxaliplatin intensification of systemic chemotherapy with FOLFIRI for patients with unresectable peritoneal carcinomatosis.
  • Principal investigator of the phase I “FLUOCAR” study evaluating the toxicity of SGM 101, anti-ACE monoclonal antibody associated with a fluorochrome, for the intraoperative detection of peritoneal carcinomatosis of colorectal origin
  • Multicentric collaborations as a leading researcher in ICM in numerous clinical studies in the enviroment of peritoneal carcinomatosis: HIPOVA-1, ESTOK-01, PIPOX, GASTRICHIP, CHIPOR.


Liver metastases:

  • Surgical researcher of the METHEP 1 and 2 and PACHA01 studies
  • Desarrollo de un programa de investigación multidisciplinario entre cirugía oncológica, radiología intervencionista y medicina nuclear sobre la función hepática del higado restante después de una hepatectomía compleja PHRC B.Guiu, E Deshayes, F.Quénet: estudio HYPER-LIV 01: embolización simultánea portal y sus-hepática versus embolización portal sola para hipertrofiar el futuro hígado que queda antes de la resección hepática mayor en hígado no cirrótico: ensayo multicéntrico aleatorizado comparativo de fase 2
  • Development of a multidisciplinary research program between oncological surgery, interventional radiology and nuclear medicine on the liver function of the remaining liver after a complex hepatectomy PHRC B.Guiu, E Deshayes, F.Quénet: study HYPER-LIV 01: portal simultaneous embolization and sus-hepatic versus portal embolization alone to hypertrophy the future liver remaining before major liver resection in non-cirrhotic liver: a multicenter randomized comparative phase 2 trial.

 Translational research:

  • Member of the research team INSERM U896, “Molecular bases of resistance to tumor suppressors”, responsible P.Martineau, Instituto de Investigación del Cáncer de Montpellier.

Work in progress:

  • Contribution of mass spectrometry to intraperitoneal chemohyperthermia in peritoneal carcinomatosis. Team Ch.Larroque.
  • Evaluation of the penetration of oxaliplatin in the ovaries after intraperitoneal chemohyperthermia (PROTECTOVA study).
  • Evaluation using microscopic 9 TESLA magnetic resonance imaging of the therapeutic response to PIPAC in peritoneal carcinomatosis. (PIPAC MR Study).
  • Retrospective evaluation of histological samples of peritoneal carcinomatosis of colorectal, morphological, phenotypic origin and biomolecular profile with the aim of defining, characterizing and dismembering different anatomo-clinical entities with different prognosis and behavior. TRANS-PRODIGE 7 study in collaboration with F.Bibeau (Caen)

Computer engineering research

  • Adaptation to augmented reality in open hepatic surgery or laparoscopic: collaboration with the computer research group CIMNE (international center for numerical methods in engineering) Ignacio Valero López, Barcelona.

Cancer network: member of the scientific committee of the RENAPE and BIGRENAPE networks.


Savantes Societies: Member of the Board of Directors of SFCD (French Society of Digestive Surgery).

 

Industrial associations:

  • Contract consultant for the development of new surgical materials for laboratories. Ethicon and Gamida
  • Consultant for Sanofi and Novartis laboratories.
  • Collaboration with foreign centers: Associate surgeon and founding member of the “J.Torrent Institute, Surgical Oncology” (Quiron Salud) in Barcelona.
  • CHAIRMAN (2018) of the European High Course of the European Society of Surgical Oncology (ESSO) for teaching the management of peritoneal carcinomatosis (ESI Hamburg).
  • Professor DIU Peritoneal Carcinomatosis (Pr Glehen, Pr Pocard)
  • Professor in the DESC of Cancerology
  • Unit 2 of the Department of Surgery of the ICM is a campus of international practices that validate the PSOGI ​​(peritoneal surface oncology group international)

Publications: Pub Med au 09/2018

  • Colorectal peritoneal carcinomatosis: What is the future of HIPEC? Quénet F. Eur J Surg Oncol. 2018 Aug 27. pii: S0748-7983(18)31283-6. doi: 10.1016/j.ejso.2018.08.009.
  • A UNICANCER phase III trial of Hyperthermic Intra-peritoneal Chemotherapy (HIPEC) for Colorectal Peritoneal Carcinomatosis.
  • Prodige 7 – ACCORD 15 trial. NCT00769405, N° EudraCT : 2006-006175-2 Quenet F, Elias, D, Roca L, Goéré D, Ghouti L, Pocard M, Facy O, Arvieux C, Lorimier G, Pezet D, Marchal F, Loi V, Meeus P, de Forges H, Stanbury T, Paineau P, Glehen O. J Clin Oncol 36, 2018 (suppl; abstr LBA3503)
  • Cytoreductive surgery and HIPEC improve survival compared to palliative chemotherapy for biliary carcinoma with peritoneal metastasis: A multi-institutional cohort from PSOGI and BIG RENAPE groups. Amblard I, Mercier F, Bartlett DL, Ahrendt SA, Lee KW, Zeh HJ, Levine EA, Baratti D, Deraco M, Piso P, Morris DL, Rau B, Tentes AAK, Tuech JJ, Quenet F, Akaishi E, Pocard M, Yonemura Y, Lorimier G, Delroeux D, Villeneuve L, Glehen O, Passot G; PSOGI and BIG RENAPE working groups. Eur J Surg Oncol. 2018 Sep;44(9):1378-1383. doi: 10.1016/j.ejso.2018.04.023. Epub 2018 Jun 19.
  • Impact of Combination Chemotherapy in Peritoneal Mesothelioma Hyperthermic Intraperitoneal Chemotherapy (HIPEC): The RENAPE Study. Malgras B, Gayat E, Aoun O, Lo Dico R, Eveno C, Pautrat K, Delhorme JB, Passot G, Marchal F, Sgarbura O, Ferron G, Goéré D, Andre T, Pocard M; RENAPE Network. Ann Surg Oncol. 2018 Oct;25(11):3271-3279. doi: 10.1245/s10434-018-6631-2. Epub 2018 Jul 5.
  • Is there an oncological interest in the combination of CRS/HIPEC for peritoneal carcinomatosis of HCC? Results of a multicenter international study. Mehta S, Schwarz L, Spiliotis J, Hsieh MC, Akaishi EH, Goere D, Sugarbaker PH, Baratti D, Quenet F, Bartlett DL, Villeneuve L, Kepenekian V; PSOGI and BIG-RENAPE Working Groups. Eur J Surg Oncol. 2018 May 28. pii: S0748-7983(18)31075-8. doi: 10.1016/j.ejso.2018.05.021.
  • Peritoneal Carcinomatosis of Rare Ovarian Origin Treated by Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: A Multi-Institutional Cohort from PSOGI and BIG-RENAPE. Mercier F, Bakrin N, Bartlett DL, Goere D, Quenet F, Dumont F, Heyd B, Abboud K, Marolho C, Villeneuve L, Glehen O; PSOGI Working Group; BIG-RENAPE Working Group. Ann Surg Oncol. 2018 Jun;25(6):1668-1675. doi: 10.1245/s10434-018-6464-z. Epub 2018 Apr 10.
  • Multicentre study of laparoscopic or open assessment of the peritoneal cancer index (BIG-RENAPE). Passot G, Dumont F, Goéré D, Arvieux C, Rousset P, Regimbeau JM, Elias D, Villeneuve L, Glehen O; BIG-RENAPE Surgery Working Group. Br J Surg. 2018 May;105(6):663-667. doi: 10.1002/bjs.10723. Epub 2018 Mar 26.
  • Cytoreductive Surgery Plus Hyperthermic Intraperitoneal Chemotherapy for Peritoneal Metastases From a Small Bowel Adenocarcinoma: Multi-Institutional Experience. Liu Y, Yonemura Y, Levine EA, Glehen O, Goere D, Elias D, Morris DL, Sugarbaker PH, Tuech JJ, Cashin P, Spiliotis JD, de Hingh I, Ceelen W, Baumgartner JM, Piso P, Katayama K, Deraco M, Kusamura S, Pocard M, Quenet F, Fushita S; BIG-RENAPE Group. Ann Surg Oncol. 2018 May;25(5):1184-1192. doi: 10.1245/s10434-018-6369-x. Epub 2018 Feb 26.
  • Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for pseudomyxoma peritonei of appendicular and extra-appendicular origin. Delhorme JB, Severac F, Averous G, Glehen O, Passot G, Bakrin N, Marchal F, Pocard M, Lo Dico R, Eveno C, Carrere S, Sgarbura O, Quenet F, Ferron G, Goéré D, Brigand C; French National Network of Peritoneal Surface Malignancies (RENAPE). Br J Surg. 2018 May;105(6):668-676. doi: 10.1002/bjs.10716. Epub 2018 Feb 7.
  • When and Who Should Perform Epithelial Ovarian Cancer Surgery? Escayola C, Torrent JJ, Ferron G, Quenet F, Querleu D. Int J Gynecol Cancer. 2018 Mar;28(3):594-599. doi: 10.1097/IGC.0000000000001188.
  • Peritoneal Carcinomatosis of Urachus Origin Treated by Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC): An International Registry of 36 Patients. Mercier F, Passot G, Villeneuve L, Levine EA, Yonemura Y, Goéré D, Sugarbaker PH, Marolho C, Bartlett DL, Glehen O; BIG-RENAPE Working Group. Ann Surg Oncol. 2018 Apr;25(4):1094-1100. doi: 10.1245/s10434-017-6299-z. Epub 2017 Dec 13.
  • Impact of RAS Mutations in Metastatic Colorectal Cancer After Potentially Curative Resection: Does Site of Metastases Matter? Passot G, Kim BJ, Glehen O, Mehran RJ, Kopetz SE, Goere D, Overman MJ, Pocard M, Marchal F, Conrad C, Aloia TA, Vauthey JN, Chun YS; BIG-RENAPE Working Group. Ann Surg Oncol. 2018 Jan;25(1):179-187. doi: 10.1245/s10434-017-6141-7. Epub 2017 Oct 25.
  • Multicentric initial experience with the use of the pressurized intraperitoneal aerosol chemotherapy (PIPAC) in the management of unresectable peritoneal carcinomatosis. Alyami M, Gagniere J, Sgarbura O, Cabelguenne D, Villeneuve L, Pezet D, Quenet F, Glehen O, Bakrin N, Passot G. Eur J Surg Oncol. 2017 Nov;43(11):2178-2183. doi: 10.1016/j.ejso.2017.09.010. Epub 2017 Sep 21.
  • Extended Liver Venous Deprivation Leads to a Higher Increase in Liver Function that ALPPS in Early Assessment : A comment to “Sparrelid, E. et al. Dynamic Evaluation of Liver Volume and Function in Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy. Journal of Gastrointestinal Surgery (2017)”. Deshayes E, Schadde E, Piron L, Quenet F, Guiu B. J Gastrointest Surg. 2017 Oct;21(10):1754-1755. doi: 10.1007/s11605-017-3508-9. Epub 2017 Aug 7. No abstract available.
  • Immunohistochemical evaluation of two antibodies against PD-L1 and prognostic significance of PD-L1 expression in epithelioid peritoneal malignant mesothelioma: A RENAPE study. Valmary-Degano S, Colpart P, Villeneuve L, Monnien F, M’Hamdi L, Lang Averous G, Capovilla M, Bibeau F, Laverriere MH, Verriele-Beurrier V, Ben Rejeb H, Dartigues P, Hommell-Fontaine J, Gilly FN, Isaac S, Mery E; French RENAPE Network. Eur J Surg Oncol. 2017 May 18. pii: S0748-7983(17)30487-0. doi: 10.1016/j.ejso.2017.05.009.
  • SGM-101: An innovative near-infrared dye-antibody conjugate that targets CEA for fluorescence-guided surgery. Gutowski M, Framery B, Boonstra MC, Garambois V, Quenet F, Dumas K, Scherninski F, Cailler F, Vahrmeijer AL, Pèlegrin A. Surg Oncol. 2017 Jun;26(2):153-162. doi: 10.1016/j.suronc.2017.03.002. Epub 2017 Mar 9.
  • Imaged-guided liver stereotactic body radiotherapy using VMAT and real-time adaptive tumor gating. Concerns about technique and preliminary clinical results. Llacer-Moscardo C, Riou O, Azria D, Bedos L, Ailleres N, Quenet F, Rouanet P, Ychou M, Fenoglietto P. Rep Pract Oncol Radiother. 2017 Mar-Apr;22(2):141-149. doi: 10.1016/j.rpor.2016.06.004. Epub 2016 Sep 5.
  • Portal vein embolization: Present and future Piron L, Deshayes E, Escal L, Souche R, Herrero A, Pierredon-Foulongne MA, Assenat E, le Lam N, Quenet F, Guiu B. Bull Cancer. 2017 May;104(5):407-416. doi: 10.1016/j.bulcan.2017.03.009. Epub 2017 May 3. Review. French.
  • The RENAPE observational registry: rationale and framework of the rare peritoneal tumors French patient registry. Villeneuve L, Passot G, Glehen O, Isaac S, Bibeau F, Rousset P, Gilly FN; RENAPE Network. Orphanet J Rare Dis. 2017 Feb 17;12(1):37. doi: 10.1186/s13023-017-0571-y.
  • Extended liver venous deprivation before major hepatectomy induces marked and very rapid increase in future liver remnant function. Guiu B, Quenet F, Escal L, Bibeau F, Piron L, Rouanet P, Fabre JM, Jacquet E, Denys A, Kotzki PO, Verzilli D, Deshayes E. Eur Radiol. 2017 Aug;27(8):3343-3352. doi: 10.1007/s00330-017-4744-9. Epub 2017 Jan 18.
  • Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Peritoneal Carcinomatosis in the Elderly: A Case-Controlled, Multicenter Study. Alyami M, Lundberg P, Kepenekian V, Goéré D, Bereder JM, Msika S, Lorimier G, Quenet F, Ferron G, Thibaudeau E, Abboud K, Lo Dico R, Delroeux D, Brigand C, Arvieux C, Marchal F, Tuech JJ, Guilloit JM, Guyon F, Peyrat P, Pezet D, Ortega-Deballon P, Zinzindohoue F, de Chaisemartin C, Kianmanesh R, Glehen O, Passot G; BIG-RENAPE and RENAPE Working Groups. Ann Surg Oncol. 2016 Dec;23(Suppl 5):737-745. Epub 2016 Sep 6.
  • Diffuse malignant peritoneal mesothelioma: Evaluation of systemic chemotherapy with comprehensive treatment through the RENAPE Database: Multi-Institutional Retrospective Study. Kepenekian V, Elias D, Passot G, Mery E, Goere D, Delroeux D, Quenet F, Ferron G, Pezet D, Guilloit JM, Meeus P, Pocard M, Bereder JM, Abboud K, Arvieux C, Brigand C, Marchal F, Classe JM, Lorimier G, De Chaisemartin C, Guyon F, Mariani P, Ortega-Deballon P, Isaac S, Maurice C, Gilly FN, Glehen O; French Network for Rare Peritoneal Malignancies (RENAPE). Eur J Cancer. 2016 Sep;65:69-79. doi: 10.1016/j.ejca.2016.06.002. Epub 2016 Jul 26.
  • Oncovascular compartmental resection for retroperitoneal soft tissue sarcoma with vascular involvement. Bertrand MM, Carrère S, Delmond L, Mehta S, Rouanet P, Canaud L, Alric P, Quénet F. J Vasc Surg. 2016 Oct;64(4):1033-41. doi: 10.1016/j.jvs.2016.04.006. Epub 2016 Jun 30.
  • Results of a multicenter phase I dose-finding trial of hyperthermic intraperitoneal cisplatin after neoadjuvant chemotherapy and complete cytoreductive surgery and followed by maintenance bevacizumab in initially unresectable ovarian cancer. Gouy S, Ferron G, Glehen O, Bayar A, Marchal F, Pomel C, Quenet F, Bereder JM, Le Deley MC, Morice P. Gynecol Oncol. 2016 Aug;142(2):237-42. doi: 10.1016/j.ygyno.2016.05.032. Epub 2016 Jun 2.
  • Simultaneous trans-hepatic portal and hepatic vein embolization before major hepatectomy: the liver venous deprivation technique. Guiu B, Chevallier P, Denys A, Delhom E, Pierredon-Foulongne MA, Rouanet P, Fabre JM, Quenet F, Herrero A, Panaro F, Baudin G, Ramos J. Eur Radiol. 2016 Dec;26(12):4259-4267. Epub 2016 Apr 18.
  • A new internet tool to report peritoneal malignancy extent. PeRitOneal MalIgnancy Stage Evaluation (PROMISE) application. Villeneuve L, Thivolet A, Bakrin N, Mohamed F, Isaac S, Valette PJ, Glehen O, Rousset P; BIG-RENAPE and RENAPE Working Groups. Eur J Surg Oncol. 2016 Jun;42(6):877-82. doi: 10.1016/j.ejso.2016.03.015. Epub 2016 Mar 28.
  • Cytoreductive Surgery Combined with Hyperthermic Intraperitoneal Chemotherapy with Oxaliplatin Increases the Risk of Postoperative Hemorrhagic Complications: Analysis of Predictive Factors. Charrier T, Passot G, Peron J, Maurice C, Gocevska S, Quénet F, Eveno C, Pocard M, Goere D, Elias D, Ortega-Deballon P, Vaudoyer D, Cotte E, Glehen O. Ann Surg Oncol. 2016 Jul;23(7):2315-22. doi: 10.1245/s10434-016-5143-1. Epub 2016 Feb 26.
  • Robotic Versus Laparoscopic Total Mesorectal Excision (TME) for Sphincter-Saving Surgery: Is There Any Difference in the Transanal TME Rectal Approach? : A Single-Center Series of 120 Consecutive Patients. Colombo PE, Bertrand MM, Alline M, Boulay E, Mourregot A, Carrère S, Quénet F, Jarlier M, Rouanet P. Ann Surg Oncol. 2016 May;23(5):1594-600. doi: 10.1245/s10434-015-5048-4. Epub 2015 Dec 29.
  • Standardized single docking, four arms and fully robotic proctectomy for rectal cancer: the key points are the ports and arms placement. Bertrand MM, Colombo PE, Mourregot A, Traore D, Carrère S, Quénet F, Rouanet P. J Robot Surg. 2016 Jun;10(2):171-4. doi: 10.1007/s11701-015-0551-y. Epub 2015 Dec 8.
  • Professional risks when carrying out cytoreductive surgery for peritoneal malignancy with hyperthermic intraperitoneal chemotherapy (HIPEC): A French multicentric survey. Ferron G, Simon L, Guyon F, Glehen O, Goere D, Elias D, Pocard M, Gladieff L, Bereder JM, Brigand C, Classe JM, Guilloit JM, Quenet F, Abboud K, Arvieux C, Bibeau F, De Chaisemartin C, Delroeux D, Durand-Fontanier S, Goasguen N, Gouthi L, Heyd B, Kianmanesh R, Leblanc E, Loi V, Lorimier G, Marchal F, Mariani P, Mariette C, Meeus P, Msika S, Ortega-Deballon P, Paineau J, Pezet D, Piessen G, Pirro N, Pomel C, Porcheron J, Pourcher G, Rat P, Regimbeau JM, Sabbagh C, Thibaudeau E, Torrent JJ, Tougeron D, Tuech JJ, Zinzindohoue F, Lundberg P, Herin F, Villeneuve L; BIG-RENAPE Working Group. Eur J Surg Oncol. 2015 Oct;41(10):1361-7. doi: 10.1016/j.ejso.2015.07.012. Epub 2015 Jul 29.
  • Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for First Relapse of Ovarian Cancer. Classe JM, Glehen O, Decullier E, Bereder JM, Msika S, Lorimier G, Abboud K, Meeus P, Ferron G, Quenet F, Marchal F, Gouy S, Pomel C, Pocard M, Guyon F, Bakrin N; French Oncologic and Gynecologic HIPEC Group. Anticancer Res. 2015 Sep;35(9):4997-5005.
  • Multicentre study of the learning curve and surgical performance of cytoreductive surgery with intraperitoneal chemotherapy for pseudomyxoma peritonei. Kusamura S, Moran BJ, Sugarbaker PH, Levine EA, Elias D, Baratti D, Morris DL, Sardi A, Glehen O, Deraco M; Peritoneal Surface Oncology Group International (PSOGI); Peritoneal Surface Oncology Group International PSOGI. Br J Surg. 2014 Oct 20. doi: 10.1002/bjs.9674.
  • Impact of neoadjuvant chemotherapy cycles prior to interval surgery in patients with advanced epithelial ovarian cancer. Colombo PE, Labaki M, Fabbro M, Bertrand M, Mourregot A, Gutowski M, Saint-Aubert B, Quenet F, Rouanet P, Mollevi C. Gynecol Oncol. 2014 Sep 16. pii: S0090-8258(14)01305-5. doi:
  • Complementarity of MALDI and LA ICP mass spectrometry for platinum anticancer imaging in human tumor. Bianga J, Bouslimani A, Bec N, Quenet F, Mounicou S, Szpunar J, Bouyssiere B, Lobinski R, Larroque C. Metallomics. 2014 Aug;6(8):1382-6. doi: 10.1039/c4mt00131a.
  • [Impact of surgery in management of pancreatic metastases of renal cell cancer]. Bertrand J, Saint-Aubert B, Joly E, Philippe C, Quenet F, Carrere S, Rouanet P, Domergue J. Prog Urol. 2014 Apr;24(5):307-12. doi: 10.1016/j.purol.2013.09.028. Epub 2013 Oct 25. French.
  • Peritoneal carcinomatosis treated with cytoreductive surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for advanced ovarian carcinoma: a French multicentre retrospective cohort study of 566 patients. Bakrin N, Bereder JM, Decullier E, Classe JM, Msika S, Lorimier G, Abboud K, Meeus P, Ferron G, Quenet F, Marchal F, Gouy S, Morice P, Pomel C, Pocard M, Guyon F, Porcheron J, Glehen O; FROGHI (FRench Oncologic and Gynecologic HIPEC) Group. Eur J Surg Oncol. 2013 Dec;39(12):1435-43. doi: 10.1016/j.ejso.2013.09.030. Epub 2013 Oct 17.
  • A randomized phase II trial of three intensified chemotherapy regimens in first-line treatment of colorectal cancer patients with initially unresectable or not optimally resectable liver metastases. The METHEP trial. Ychou M, Rivoire M, Thezenas S, Quenet F, Delpero JR, Rebischung C, Letoublon C, Guimbaud R, Francois E, Ducreux M, Desseigne F, Fabre JM, Assenat E. Ann Surg Oncol. 2013 Dec;20(13):4289-97. doi: 10.1245/s10434-013-3217-x. Epub 2013 Aug 17.
  • Comparison between internalizing anti-HER2 mAbs and non-internalizing anti-CEA mAbs in alpha-radioimmunotherapy of small volume peritoneal carcinomatosis using 212Pb. Boudousq V, Bobyk L, Busson M, Garambois V, Jarlier M, Charalambatou P, Pèlegrin A, Paillas S, Chouin N, Quenet F, Maquaire P, Torgue J, Navarro-Teulon I, Pouget JP. PLoS One. 2013 Jul 29;8(7):e69613. doi: 10.1371/journal.pone.0069613. Print 2013.
  • Primary peritoneal serous carcinoma treated by cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy. A multi-institutional study of 36 patients. Bakrin N, Gilly FN, Baratti D, Bereder JM, Quenet F, Lorimier G, Mohamed F, Elias D, Glehen O; Association Française de Chirurgie. Eur J Surg Oncol. 2013 Jul;39(7):742-7. doi: 10.1016/j.ejso.2013.02.018. Epub 2013 Mar 16.
  • Transanal endoscopic proctectomy: an innovative procedure for difficult resection of rectal tumors in men with narrow pelvis. Rouanet P, Mourregot A, Azar CC, Carrere S, Gutowski M, Quenet F, Saint-Aubert B, Colombo PE. Dis Colon Rectum. 2013 Apr;56(4):408-15. doi: 10.1097/DCR.0b013e3182756fa0.
  • Use of bioresorbable membranes to reduce abdominal and perihepatic adhesions in 2-stage hepatectomy of liver metastases from colorectal cancer: results of a prospective, randomized controlled phase II trial. Dupré A, Lefranc A, Buc E, Delpero JR, Quenet F, Passot G, Evrard S, Rivoire M. Ann Surg. 2013 Jul;258(1):30-6. doi: 10.1097/SLA.0b013e3182854949.
  • Current status and future directions in the treatment of peritoneal dissemination from colorectal carcinoma. Elias D, Quenet F, Goéré D. Surg Oncol Clin N Am. 2012 Oct;21(4):611-23.
  • [Management of colorectal liver metastases after induction treatment. The pathologist’s role in 2011]. Bibeau F, Rivière B, Boissière F, Jourdan MF, Bodin X, Perrault V, Cantos C, Lavaill R, Ychou M, Quenet F, Terris B. Ann Pathol. 2011 Dec;31(6):427-32.
  • Results of two bi-institutional prospective studies using intraperitoneal oxaliplatin with or without irinotecan during HIPEC after cytoreductive surgery for colorectal carcinomatosis. Quenet F, Goéré D, Mehta SS, Roca L, Dumont F, Hessissen M, Saint-Aubert B, Elias D. Ann Surg. 2011 Aug;254(2):294-301.
  • [Natural history and management of retroperitoneal sarcoma: Review of the literature by the Oncology committee of the French association of urology]. Avancès C, Camparo P, Quenet F, Durand X, Culine S, Sèbe P, Soulié M, Rigaud J; Comité de Cancérologie de l’Association Française d’Urologie – groupe Organes Génitaux Externes (CCAFU-OGE). Prog Urol. 2011 Jul;21(7):441-7.
  • Brief intraperitoneal radioimmunotherapy of small peritoneal carcinomatosis using high activities of noninternalizing 125I-labeled monoclonal antibodies. Boudousq V, Ricaud S, Garambois V, Bascoul-Mollevi C, Boutaleb S, Busson M, Quenet F, Colombo PE, Bardiès M, Kotzki PO, Navarro-Teulon I, Pèlegrin A, Pouget JP. J Nucl Med. 2010 Nov;51(11):1748-55.
  • Feasibility study of volumetric modulated arc therapy for the treatment of retroperitoneal sarcomas. Llacer-Moscardo C, Quenet F, Azria D, Fenoglietto P. Radiat Oncol. 2010 Sep 20;5:83.
  • Toward curative treatment of peritoneal carcinomatosis from nonovarian origin by cytoreductive surgery combined with perioperative intraperitoneal chemotherapy: a multi-institutional study of 1,290 patients. Glehen O, Gilly FN, Boutitie F, Bereder JM, Quenet F, Sideris L, Mansvelt B, Lorimier G, Msika S, Elias D; French Surgical Association. Cancer. 2010 Dec 15;116(24):5608-18.
  • Hyperthermic intra-peritoneal chemotherapy using oxaliplatin as consolidation therapy for advanced epithelial ovarian carcinoma. Results of a phase II prospective multicentre trial. CHIPOVAC study. Pomel C, Ferron G, Lorimier G, Rey A, Lhomme C, Classe JM, Bereder JM, Quenet F, Meeus P, Marchal F, Morice P, Elias D. Eur J Surg Oncol. 2010 Jun;36(6):589-93.
  • A comparative study of complete cytoreductive surgery plus intraperitoneal chemotherapy to treat peritoneal dissemination from colon, rectum, small bowel, and nonpseudomyxoma appendix. Elias D, Glehen O, Pocard M, Quenet F, Goéré D, Arvieux C, Rat P, Gilly F; Association Française de Chirurgie. Ann Surg. 2010 May;251(5):896-901.
  • Peritoneal carcinomatosis from gastric cancer: a multi-institutional study of 159 patients treated by cytoreductive surgery combined with perioperative intraperitoneal chemotherapy. Glehen O, Gilly FN, Arvieux C, Cotte E, Boutitie F, Mansvelt B, Bereder JM, Lorimier G, Quenet F, Elias D; Association Française de Chirurgie. Ann Surg Oncol. 2010 Sep;17(9):2370-7
  • Pseudomyxoma peritonei: a French multicentric study of 301 patients treated with cytoreductive surgery and intraperitoneal chemotherapy. Elias D, Gilly F, Quenet F, Bereder JM, Sidéris L, Mansvelt B, Lorimier G, Glehen O; Association Française de Chirurgie. Eur J Surg Oncol. 2010 May;36(5):456-62.
  • Peritoneal colorectal carcinomatosis treated with surgery and perioperative intraperitoneal chemotherapy: retrospective analysis of 523 patients from a multicentric French study. Elias D, Gilly F, Boutitie F, Quenet F, Bereder JM, Mansvelt B, Lorimier G, Dubè P, Glehen O. J Clin Oncol. 2010 Jan 1;28(1):63-8. doi: 10.1200/JCO.2009.23.9285. Epub 2009 Nov 16. Erratum in: J Clin Oncol. 2010 Apr 1;28(10):1808.
  • Total laparoscopic radical hysterectomy for locally advanced cervical carcinoma (stages IIB, IIA and bulky stages IB) after concurrent chemoradiation therapy: surgical morbidity and oncological results. Colombo PE, Bertrand MM, Gutowski M, Mourregot A, Fabbro M, Saint-Aubert B, Quenet F, Gourgou S, Kerr C, Rouanet P. Gynecol Oncol. 2009 Sep;114(3):404-9.
  • [Spontaneous recovery from extensive hepatic ischemia following an extended pancreaticoduodenectomy]. Colombo PE, Bertrand MM, Mourregot A, Gutowski M, Quenet F, Saint-Aubert B, Rouanet P. J Chir (Paris). 2008 Jul-Aug;145(4):404-6.
  • Adjuvant radioimmunotherapy trial with iodine-131-labeled anti-carcinoembryonic antigen monoclonal antibody F6 F(ab’)2 after resection of liver metastases from colorectal cancer. Ychou M, Azria D, Menkarios C, Faurous P, Quenet F, Saint-Aubert B, Rouanet P, Pèlegrin M, Bascoul-Mollevi C, Guerreau D, Saccavini JC, Mach JP, Artus JC, Pèlegrin A. Clin Cancer Res. 2008 Jun 1;14(11):3487-93.
  • Aggressive surgical strategies in advanced ovarian cancer: a monocentric study of 203 stage IIIC and IV patients. Colombo PE, Mourregot A, Fabbro M, Gutowski M, Saint-Aubert B, Quenet F, Gourgou S, Rouanet P. Eur J Surg Oncol. 2009 Feb;35(2):135-43
  • [Expert agreement on the minimal descriptive surgical report for peritoneal cancer]. Bereder JM, Classe JM, Ducreux M, Elias D, Ferron G, Gilly F, Glehen O, Lorimier G, Morice P, Msika S, Pocard M, Quenet F. J Chir (Paris). 2007 Sep-Oct;144(5):463.
  • Tritherapy with fluorouracil/leucovorin, irinotecan and oxaliplatin (FOLFIRINOX): a phase II study in colorectal cancer patients with non-resectable liver metastases. Ychou M, Viret F, Kramar A, Desseigne F, Mitry E, Guimbaud R, Delpero JR, Rivoire M, Quénet F, Portier G, Nordlinger B. Cancer Chemother Pharmacol. 2008 Jul;62(2):195-201.
  • [Positive sentinel node biopsy in breast cancer: is axillary surgery necessary in all cases?]. Trentini F, Saint-Aubert B, Quenet F, Gutowski M, Bibeau F, Simony-Lafontaine J, Chateau MC, Pourquier D, Eslimani M, Delfour C, Gourgou S, Thezenas S, Rouanet P. Bull Cancer. 2007 Jul;94(7):700-4.
  • The value of endoscopic rectal ultrasound in predicting the lateral clearance and outcome in patients with lower-third rectal adenocarcinoma. Assenat E, Thézenas S, Samalin E, Bibeau F, Portales F, Azria D, Quenet F, Rouanet P, Saint Aubert B, Senesse P. Endoscopy. 2007 Apr;39(4):309-13.
  • [Vascular hepatic injury following neoadjuvant treatment for a cardial adenocarcinoma]. Bibeau F, Azria D, Chateau MC, Borrelly C, Ychou M, Quenet F, Rouanet P. Gastroenterol Clin Biol. 2006 Apr;30(4):611-3.
  • Hepatic arterial oxaliplatin infusion plus intravenous chemotherapy in colorectal cancer with inoperable hepatic metastases: a trial of the gastrointestinal group of the Federation Nationale des Centres de Lutte Contre le Cancer. Ducreux M, Ychou M, Laplanche A, Gamelin E, Lasser P, Husseini F, Quenet F, Viret F, Jacob JH, Boige V, Elias D, Delperro JR, Luboinski M; gastrointestinal group of the Federation Nationale des Centres de Lutte Contre le Cancer. J Clin Oncol. 2005 Aug 1;23(22):4881-7. Epub 2005 Jul 11.
  • Surgery for esophageal cancer after concomitant radiochemotherapy: oncologic and functional results. Plaisant N, Senesse P, Azria D, Lemanski C, Ychou M, Quenet F, Saint-Aubert B, Rouanet P. World J Surg. 2005 Jan;29(1):32-8.
  • Cytoreductive surgery combined with perioperative intraperitoneal chemotherapy for the management of peritoneal carcinomatosis from colorectal cancer: a multi-institutional study. Glehen O, Kwiatkowski F, Sugarbaker PH, Elias D, Levine EA, De Simone M, Barone R, Yonemura Y, Cavaliere F, Quenet F, Gutman M, Tentes AA, Lorimier G, Bernard JL, Bereder JM, Porcheron J, Gomez-Portilla A, Shen P, Deraco M, Rat P. J Clin Oncol. 2004 Aug 15;22(16):3284-92.
  • [Secondary debulking surgery and intraperitoneal chemotherapy in advanced or recurrent epithelial ovarian cancer].  Plaisant N, Quenet F, Fabbro M, Gourgou S, Gutowski M, Saint-Aubert B, Rouanet P. Gynecol Obstet Fertil. 2004 May;32(5):391-7.
  • Letter to the Editor. Påhlman L, Rouanet P, Saint-Aubert B, Lemanski C, Senesse P, Gourgou S, Quenet F, Ychou M, Kramar A, Dubois J. Dis Colon Rectum. 2002 Mar;45(3):313-315.
  • Restorative and nonrestorative surgery for low rectal cancer after high-dose radiation: long-term oncologic and functional results. Rouanet P, Saint-Aubert B, Lemanski C, Senesse P, Gourgou S, Quenet F, Ycholu M, Kramar A, Dubois J. Dis Colon Rectum. 2002 Mar;45(3):305-13; discussion 313-5.
  • Contribution of endorectal ultrasonography in preoperative evaluation for very low rectal cancer]. Senesse P, Khemissa F, Lemanski C, Masson B, Quenet F, Saint-Aubert B, Simony J, Ychou M, Dubois JB, Rouanet P. Gastroenterol Clin Biol. 2001 Jan;25(1):24-8.
  • Antiphospholipid antibodies in alcoholic liver disease are influenced by histological damage but not by alcohol consumption. Perney P, Biron-Andréani C, Joomaye Z, Fabbro-Peray P, Quénet F, Schved JF, Blanc F. Lupus. 2000;9(6):451-5.
  • [Update on gastroenterology]. Ychou M, Senesse P, Quénet F. Bull Cancer. 2000 Jun;87(6):455-61.
  • [Update on gastroenterology]. Ychou M, Senesse P, Quenet F. Bull Cancer. 1998 Jan;85(1):37-41.
  • [Value of percutaneous hepatic biopsy in the diagnosis of presumed benign tumors of the liver]. Khiari A, Navarro F, Fabre JM, Duchene D, Quenet F, Ducatez C, Ramos J, Pradel J, Domergue J. Ann Chir. 1996;50(7):532-7.
  • Posttraumatic pancreatic fistula cured by endoprosthesis in the pancreatic duct. Fabre JM, Bauret P, Prudhomme M, Quenet F, Noel P, Baumel H, Michel H, Domergue J. Am J Gastroenterol. 1995 May;90(5):804-6.
  • Donor liver glutathion S-transferase activity during graft preservation. Pageaux GP, Perrigault PF, Navarro F, Blanc P, Noel P, Quenet F, Maurel P, Larrey D, Michel H. Transplant Proc. 1995 Apr;27(2):1656-7.
  • [Amyloidosis of the gallbladder. An unusual localization]. Remy AJ, Perney P, Bourat L, Ramos J, Marty M, Cabaniols H, Durand L, Quenet F, Blanc F. Gastroenterol Clin Biol. 1995 Feb;19(2):215-7.
  • [Treatment of colorectal cancers]. Messens D, Fabre JM, Quenet F, Noël P. Soins Chir. 1994 Dec-1995 Jan;(166-167):8-17.
  • [Colorectal cancers. Postoperative surveillance and complications]. Fabre JM, Quenet F. Soins Chir. 1994 Dec-1995 Jan;(166-167):18-21.
  • [Resection anastomosis of the small intestine by celioscopy in swine. Comparative experimental study between manual and mechanical anastomosis]. Noël P, Fagot H, Fabre JM, Mann C, Quenet F, Guillon F, Baumel H, Domergue J. Ann Chir. 1994;48(10):921-9.
  • [Appendiceal carcinoid tumor of systematic detection. When to propose right hemi-colectomy and how to monitor? Thoughts apropos of a case and review of the literature]. Rouanet P, Saingra B, Quénet F, Régnier JJ, Simony-Lafontaine J, Pujol H. Ann Chir. 1992;46(10):919-22.